REDDRESS USA, INC — ActiGraft
ActiGraft is a wound care kit that enables the caregiver to transform a patient’s whole blood into an autologous clot that is affixed to the wound, recreating the natural wound‐healing environment. It’s a point‐of‐care treatment alternative to expensive synthetic graft options and using only 10 ml of a patient’s own blood. ActiGraft serves as a protective, provisional extracellular matrix (ECM) that contains the cytokines and growth factors (e.g., interleukin, transforming growth factor‐β, platelet‐derived growth factor, and vascular endothelial growth factor) released by the degranulation of activated platelets. ActiGraft also recruits endothelial cells and fibroblasts, which begin to synthesize a permanent ECM at the wound bed, in addition to inducing the migration of neutrophils, and wound macrophages. ActiGraft serves as a protective covering over the open wound, under which remodeling takes place undisturbed for seven days, as well as serves as a biologic scaffold, and as a wound microenvironment to promote healing.